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However, UBR5-dependent polyubiquitylation was less efficient when co-incubated with wild-type OTUD5 than with C224R OTUD5 (Fig

In this study, we used a computationally-guided approach to design and characterize a library of covalent fragments functionalized with a natural product-inspired 3-bromo-4,5-dihydroxazole (BDHI) electrophile

For example, changing your diet and lifestyle in a healthier way, or prescribing more in-depth research

When we further investigated conjugated BAs and their associations with anti-SGC IgG levels, we found that the association depended on the specific amino acid used for conjugation

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Perioperative dexmedetomidine improves outcomes of cardiac surgery