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The ratio of reduced glutathione (GSH) to its oxidized form (GSSG) dropped from 18.9 in young adults to 7.4 in elderly subjects

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Additionally, metformin can improve endometrial receptivity by increasing the expression of GLUT4 in the endometrium, regulating the expression of hormone receptors related to endometrial decidualization, and modulating autophagy and nucleic acid/protein transcription processes, which in turn improves the reproductive outcomes of PCOS

Intracellular amyloid toxicity induces oxytosis/ferroptosis regulated cell death