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Furthermore, it promotes efficient wound healing, accelerating the regeneration of damaged tissues for a smoother recovery process
Physiology 21 , 307315 (2006)
In phase I reactions, CYP1A1/2 and CYP3A4 oxidise estrogen to a 2-hydroxylated catechol estrogen, whereas CYP1B1 (which is constitutively expressed in the breasts, ovaries, adrenal glands, and uterus, as well as in several other tissues 13,14 converts it to 4-hydroxylated catechol estrogen 15,16
Notably, curcumin has demonstrated generally good tolerability even at high doses up to 12 g/day in clinical studies
These studies demonstrate the potential of transplanted NSCs in augmenting neurogenesis to produce neurons that integrate into different brain regions during aging and neurodegeneration
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