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In general, the secretion of synuclein in degenerating neurons is greatly increased compared with that of healthy neurons, and alpha-synuclein has enhanced immune characteristics when oxidized or nitrated

Shifting the interval to 5 or 9 days creates blood level fluctuations that can affect both efficacy and side effects

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Considering that kidney and brain dysfunction share common pathogenic factors, such as vascular endothelial injury, oxidative stress, and inflammation activation, we speculate that finerenone may achieve the cognitive preservation by suppressing the production of ROS and pro-inflammatory cytokines, and could improve cerebral microvascular function by alleviating endothelial dysfunction

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Once absorbed, it stimulates fibroblast activity, increases collagen production, and activates antioxidant enzymes