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Nasal allergy-like symptoms aggravated by ozone exposure in a concentration-dependent manner in Guinea pigs

A later animal study had similar results, linking severe B12 deficiency to increased body fat

10.1093/ajcn/68.2.311 55 MeydaniS

In addition to benefits ranging from heavy metal chelation, antioxidant and anti-inflammatory actions, they also activate nuclear factor (erythroid-derived 2)-like 2 (Nrf2), an antioxidant response element signalling pathway

Kannan R, Chakrabarti R, Tang D, Kim KJ, Kaplowitz N

Toxicology and adverse effects Silymarin acceptability is good and just a gentle gastrointestinal disturbance and mild allergic reactions, urticaria, nausea, headache, joint pain, itching, and mild laxative symptoms have been reported