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Haem can directly induce ferroptosis under the regulation of mitochondrial haem oxygenase 1 and cytoplasmic haem oxygenase

J Clin Invest (2009) 119(11):3189202.10.1172/Jci39375 278 GunnellDOkashaMSmithGDOliverSESandhuJHollyJM

Copper deficiency impairs copper-dependent enzymes, whereas copper overload promotes excessive reactive oxygen species (ROS) generation, leading to oxidative damage to lipids, proteins, and DNA [5, 6]

For example, the laccase-like activity of Fe 1 @CN-20 nanozyme remains nearly unaffected even after 45 min of pretreatment at 100 C, whereas natural laccase sharply declines at 70 C and becomes almost inactive by 80 C 156

Users report accelerated healing compared to previous similar injuries

Vitamin B12 is vital for red blood cell formation, DNA repair, and nerve function