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Not when taken at recommended doses in healthy individuals
However, one should only use these methods under medical guidance
ADAs 86th Scientific Sessions This event is one of the largest diabetes conferences in the world, bringing together over 11,000 attendees to share and learn about cutting-edge research and advancements toward cures
The study was conducted in accordance with the protocol and the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) Good Clinical Practice (GCP) guidelines, Declaration of Helsinki and applicable Swiss and European Union regulations
Although there are several membrane proteins capable of transporting glutamate, only members of EAAT are usually named as glutamate transporters. This name suggests that EAATs transport not only glutamate but also other excitatory amino acids
Because changes in basal metabolic rate play an important role in body weight homeostasis, energy expenditure (measured by indirect calorimetry) and physical activity (measured by locomotor activity) represent important parameters for gaining further mechanistic insight into anti-obesity drug effects
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