Subcutaneous may offer slightly more consistent plasma levels, but the practical difference is marginal given the compounds short half-life requiring daily dosing either way
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There is no official link between these compounds and specific adverse event reports in the UK at this time, but the absence of reported harm does not confirm safety
You should also contact your GP if: You are unable to attend scheduled maintenance injections, as missing doses can lead to symptom recurrence You develop new symptoms that might indicate other deficiencies or health problems You are planning pregnancy, as B12 requirements may change You experience persistent side effects such as headaches, dizziness, or gastrointestinal symptoms If you experience any side effects, talk to your doctor, pharmacist or nurse
Although these symptoms improved with continued treatment, they initially worsened, indicating that neurological side effects can occur during the course of treatment
PMCID: PMC11050313.