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Oncogenic PIK3CA increases the dependency of cancer cells on glutamine by upregulating the expression of mitochondrial GPT2, which catalyzes the transamination reaction that converts glutamate and pyruvate into -KG and alanine 175

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NLRP3: NLR Family Pyrin Domain Containing 3

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Possession or use of investigational drugs outside an authorized clinical trial may be illegal in your jurisdiction

To help set the stage, the chart below outlines how different ALA dosages have been used in clinical research and what kinds of results theyre associated with