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It is an unapproved drug and cannot be legally prescribed or sold over the counter, according to Operation Supplement Safety, a Department of Defense educational project

While class II requires an adenosylcobalamin cofactor and class III, a [4Fe-4S]-activating enzyme, all class I enzymes harbor a bimetallic metal site defined in the core four-helix bundle that also encodes for an aromatic residue which participates in electron transfer (Y105 in E

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