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Moreover, radical-scavenging antioxidants such as Astragenol, Acteoside, and Edaravone have demonstrated neuroprotective effects in NDDs, primarily by neutralizing ROS, promoting GSH synthesis, and maintaining GPX4 activity to alleviate neuronal ferroptosis (Xiao et al., 2025

In 2016, alcohol-related CV diseases led to almost 600,000 global deaths

Clin Cancer Res 16(13):34203430 Spiric Z, Eri Z, Eric M (2015) Significance of vascular endothelial growth factor (VEGF)-C and VEGF-D in the progression of cutaneous melanoma

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And it actually goes even to a deeper level of how the nucleus handles stress and what the nucleus does to signal the mitochondria