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Genetically distinct subsets within ANCA-associated vasculitis

Sources Varney, Jessica L., et al

GPX family is present in all cells, primarily located in the cytosolic and mitochondrial compartments, as well as the peroxisomal compartment [30] in some cells

Aging Pathobiology and Therapeutics, 2019, 1(1): 05-09

confirming MOTS-c as a promising mitochondrial-derived peptide with anti-inflammatory and metabolic effects, MOTS-c has been shown to significantly reduce pro-inflammatory markers, improve glucose utilization, and act on fat tissue in ways that make it more directly metabolic than NAD+ in this context

doi: 10.1201/9781003390008-17 Saez, Natalie J., Cristofori-Armstrong, Ben, Anangi, Raveendra and King, Glenn F