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FIGURE 6 The aforementioned results suggested that the GHK-derived peptides exerted their anti-oxidative, anti-aging, and wound-healing activities in skin cells

As a result, endometriotic cells could bypass the G2/M checkpoint and escape cell cycle arrest, promoting tumorigenesis and acquiring features of endometriosis progression

N-acetylcysteine dose-dependently improves the analgesic effect of acetaminophen on the rat hot plate test

Upon reaching the infection site, the overexpressed bacterial gelatinase degrades the gelatin core, triggering the controlled release of vancomycin and enabling site-specific antibacterial action [90]

Additionally, the peptides ability to upregulate matrix metalloproteinase inhibitors accelerates post-acne wound healing by 33% compared to untreated controls, as evidenced by a 2023 clinical trial involving 147 participants

Finally, studies of miRNAs have the potential to provide new knowledge about drug-induced mechanisms of gene regulation that may have future relevance for translational systems medicine