While the IH-dependent pro-oxidant state appears to negatively regulate both critical periods, cell-autonomous HIF1a signaling during the first critical period of adult neurogenesis appears to orchestrate adaptations that enhance the neuronal generation following termination of IH
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This limited vascularity means fewer nutrients and growth factors reach injured areas, slowing the natural repair process
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Unbekannte Langzeitkonsequenzen: Selbst wenn kurzfristig subjektive Verbesserungen wahrgenommen werden, sind mgliche kardiometabolische, immunologische oder onkologische Langzeiteffekte vielfach ungeklrt
