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Therapies aimed at decreasing visceral hypersensitivity may be helpful (eg, a low dose of an antidepressant)

For patients with significant baseline B12 depletion or documented absorption issues, methylcobalamin (the natural form) or cyanocobalamin (the synthetic form) injectionstypically 1,000 mcg monthlyprovide more direct delivery and bypass the compromised absorption pathway

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A copper peptide is essentially a small protein fragment (known as a peptide)