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It is administered by intramuscular injection every 90 days. Some early evidence suggests that DMPA may also help to shrink fibroids, and large observational studies suggest that DMPA use can help prevent fibroids altogether

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In the Retatrutide diabetes trial, gastrointestinal adverse events appeared in roughly 35 percent of treated participants, the same family of effects seen across this drug class, and no severe low-blood-sugar episodes or deaths were reported