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Interestingly, nitric oxide inhibits mitochondrial respiration by reacting with either the reduced or the oxidized binuclear site of cytochrome c oxidase, leading to ATP depletion

(Cham: Springer International Publishing), 3946

doi:10.1093/jexbot/53.372.1331

The inclusion of dietary sources in regular diet plays a decisive role in the betaine content of the body but betaine can also be synthesised from choline derivatives

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