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It is effective for patients who are unresponsive to biologics and can be combined with biologics or systemic therapies (e.g., methotrexate), offering synergy and a better safety profile

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doi: 10.1016/j.psyneuen.2015.06.002 49 GurTLShayLPalkarAVFisherSVaraljayVADowdSet al

Unapproved New Drug: Any substance that has not completed the formal FDA approval process and fails to qualify for a strict 503A or 503B exemption is classified as an unapproved new drug, the distribution of which is prohibited in interstate commerce

[DOI] [PubMed] [Google Scholar] 152.Mohammed HE, Bady Z, Haseeb ME, Aboeldahab H, Sharaf-Eldin WE, and Zaki MS

You should discuss next steps with your dermatologist