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Patients who received duloxetine (30 mg daily in the first week and 60 mg daily in the second week of each chemotherapy cycle) had significantly lower levels of some types of neuropathy than those who received placebo, but duloxetine had no effect on measures of numbness, tingling, burning, or cold sensitivity (Aghili 2024)

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Future research should therefore prioritize standardized methodologies, large-scale human intervention studies, mechanistic investigations at the molecular level, and comprehensive safety assessments to enhance the translational applicability of Spirulina in functional food systems

Marseglia, L., DAngelo, G., Manti, S., Reiter, R

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