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AQ4N (Banoxantrone) is a bioreductive prodrug that, under hypoxic conditions, is converted to AQ4, a potent DNA-binding cytotoxin and topoisomerase II inhibitor (297)

Interestingly, when 5-amino-1MQ was applied to HEK-293 cells, another widely used cell line in research derived from human embryonic kidney cells, there was no significant impact on their growth

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