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Patients with significantly suppressed baseline IGF-1 (typically below 150 ng/mL in adults over 40) tend to see the most pronounced early changes because the distance from baseline to optimized is greatest

Back to Journals Drug Design, Development and Therapy Volume 18 The Protective Effect of Roflumilast Against Acute Hepatotoxicity Caused by Methotrexate in Wistar Rats: In vivo Evaluation Authors Almalki RS Received 19 October 2023 Accepted for publication 9 February 2024 Published 15 February 2024 Volume 2024:18 Pages 453462 DOI Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Professor Anastasios Lymperopoulos Riyadh S Almalki Department of Pharmacology and Toxicology, Faculty of Pharmacy, Umm AL-Qura University, Makkah, Saudi Arabia Correspondence: Riyadh S Almalki, Department of Pharmacology and Toxicology, Faculty of Pharmacy, Umm AL-Qura University, Makkah, 23335, Saudi Arabia, Email [email protected] Introduction: Methotrexate (MTX) is one of the most widely used drugs in cancer chemotherapy and treating rheumatoid arthritis
Proc Natl Acad Sci U S A 113(3):775780
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