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Increased EPA and DHA and decreased pro-inflammatory arachidonic acid within cell membranes result in an altered expression pattern of anti-inflammatory eicosanoids and resolvins

Important: The specific Klow combination has not been systematically evaluated in clinical studies

In UK practice, monitoring is primarily based on clinical response rather than routine blood tests

anti-Bcl-2 (D55G8) rabbit mAb, 1:1000 v/v (human specific), Cell Signaling Technology, Massachusetts, USA

10.1530/REP-09-0219 112

ThermoFisher, 11320033) with 2 mM L-glutamine, 10 mM HEPES (Sigma-Aldrich, H3375-25g), 50 U ml 1 penicillinstreptomycin, 1 B27 (ThermoFisher, 12587-010), 1 N-2 (ThermoFisher, 17502-048), 50 ng ml 1 EGF (Peprotech, AF-100-15) and 100 ng ml 1 Noggin (Peprotech, 250-38)