13 , 14 GSH as a regulator of innate immunity Anti-inflammatory role of GSH in lung diseases The idea that GSH may play an anti-inflammatory role became popular in the 1990s with a study by Schreck et al 15 showing that antioxidants inhibit, whereas ROS activate, the transcription factor NF-B that commands the transcription of several inflammatory genes, 16 a role that has been confirmed in the lung
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Effect of tumor necrosis factor-induced integrin activation on Fc gamma receptor II-mediated signal transduction: relevance for activation of neutrophils by anti-proteinase 3 or anti-myeloperoxidase antibodies
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Wang, L., Wang, N., Zhang, W., Cheng, X., Yan, Z., Shao, G., Wang, X., Wang, R., & Fu, C