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INHIBITION OF LIPOLYSIS DURING REFEEDING Refeeding attenuates adipocyte lipolysis, primarily through the potent antilipolytic actions of insulin

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The kidneys are responsible for clearing excess B12 from the blood

Typical research applications include: Investigation of NNMT inhibition and its role in metabolic regulation

Collectively, this study provides a solid foundation for future exploration into the impact of NNMTi-and diet-mediated changes to the gut microbiome in obese and lean populations, as well as future targets to investigate mechanistically with NNMTi treatment