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In organisms, two systems have been developed to neutralize these compounds, including non-enzymatic and enzymatic systems

EFSA J 2017;15:e04658

474 The neocortex of Down syndrome individuals is characterised by profound (3050%) decrease in the number of neurones and neuroglia

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Taken together, we conclude that persistent disruption of ER Ca 2+ homeostasis in Ms4a15 OE and Tgn-treated cells leads to ferroptosis resistance in a manner unrelated to ER stress