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8 Conclusion Neurodegenerative disorders continue to pose an immense clinical and societal challenge, largely because effective neuroprotective agents fail to reach the brain at sufficient concentrations to exert meaningful therapeutic effects

But individual variation exists

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Fischer W, Currais A, Liang Z, Pinto A, Maher P (2019) Old age-associated phenotypic screening for Alzheimers disease drug candidates identifies sterubin as a potent neuroprotective compound from Yerba santa

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79 There was also a clear conflict of interest, as the physicians running the study were affiliated with the clinic providing (and profiting from) the peptide therapy