Abstract Acute pancreatitis (AP) is an inflammatory disease of the pancreas and a complex process involving multiple factors, with mitochondrial damage playing a crucial role
PMC4508379 Pickart L, Vasquez-Soltero JM, Margolina A
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The exocrine pancreas with its huge rate of protein synthesis is particularly vulnerable when subjected to congestion in the busy protein-trafficking lanes - an inevitable consequence of pancreastasis episodes, despite the acinar cells best efforts to compensate by endocrine re-routing of newly synthesised enzymes