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Important milestones in the GHK-Cu literature include the original 1973 identification of GHK as a plasma-derived cell proliferation factor, the recognition of the copper-binding role in the late 1970s, the wound healing and collagen research of the 1980s and 1990s, the establishment of GHK-Cu as a cosmetic ingredient in the 1990s and 2000s, and the transcriptomic expansion of the research literature in the 2000s and 2010s
Skin color measurements were conducted at baseline and biweekly for eight weeks using two devices: Mexameter Measured melanin index (MI)
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Effect of coffee in lipopolysaccharide-induced indoleamine 2,3- dioxygenase activation and depressive-like behavior in mice
This leads to dull skin, hyperpigmentation, and other health concerns
