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Future studies should prioritize (1) isolating and characterizing the active compounds within these botanicals, (2) elucidating their precise molecular targets (e.g., thyroid peroxidase, sodium-iodide symporter, cytokine signaling pathways), and (3) conducting well-designed controlled clinical trials to rigorously evaluate their safety and efficacy in human patients

Further preclinical and clinical studies could provide evidence for EGCGs translational potential in TBI management

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The Khavinson and Ashmarin groups systematised it on Russian bioactive peptides

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