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Impact of External Loads External forces, including valgus stress and axial loading, significantly increase ACL loading, particularly during dynamic activities like cutting maneuvers and sidestepping
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Liu PS, Chen YT, Li X, Hsueh PC, Tzeng SF, Chen H, et al
They demonstrated that the addition of human umbilical cordderived MSC-EVs to single follicles isolated from aged mice promoted follicle survival, enhanced granulosa cell proliferation, and improved oocyte quality ( Overall, in vitro models reveal the strong context dependency of EV-based interventions, showing that EV effects on ovarian cells are highly sensitive to dose, exposure time, EV source, and the applied stress or aging paradigm
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