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Intensive research efforts are required to meet the demand of identifying novel eryptosis-associated kinases and investigating their potential pharmaceutical targetability

Astrocytes also exhibit dysfunctional phenotypes, including impaired potassium and glutamate buffering, which further compromise neuronal health

indeterminate zone , then doctors can do one of the secondary (functional) tests

The first BBB organoids consisted of human endothelial cells, astrocytes, and pericytes, which self-assemble under low-adherence conditions (Urich et al., 2013)

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BSO has also been used in human clinical trials for cancer, where it caused low grade toxicity 30 , suggesting it is not highly cytotoxic