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In addition to its effects on enzyme activity, insulin exerts effects on the transcription of numerous genes, effects that are primarily mediated by regulating the activity of the transcriptional co-activator, PGC-1
Mechanisms and therapeutic implications of cellular senescence in osteoarthritis
doi: 10.1136/bmj.e5085 [DOI] [PMC free article] [PubMed] [Google Scholar] 85.Bal BS, Finelli FC, Shope TR, et al
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