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DNA and Cell Biology [J], 2012, 40 (2): 172-183

Despite promising in vitro results, the study addresses limitations such as poor oral bioavailability and rapid metabolism

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Additionally, biofilm viability decreased by more than 50% across all species

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Differentiated cells express key hepatocyte markersincluding albumin, tyrosine aminotransferase (TAT), and cytokeratin-18 (CK18)at both the mRNA and protein levels and exhibit essential hepatocyte functions, such as albumin secretion, glycogen storage, and cytochrome P450 7A1 expression, thereby effectively mimicking the metabolic and detoxification functions of mature hepatocytes (Malik et al., 2018)