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Oligodendrocytes enhance axonal energy metabolism by deacetylation of mitochondrial proteins through transcellular delivery of SIRT2

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Patients with AD undergo a significant loss of neurons and synaptic connections, including in the entorhinal cortex and hippocampus (Braak et al., 2006)

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The most notable finding was that the weight loss was specifically fat loss, particularly in the abdominal area