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Lippi et al

Acetylcarnitine can also improve mitochondrial biosynthesis, quality control and dynamics by increasing the levels of peroxisome proliferator-activated receptor coactivator 1 (PGC-1) and mitochondrial DNA (mtDNA) [16]

J Control Release 352:1524

Researchers exploring peptides for weight loss and muscle gain often look at this balance carefully

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Insulin-like growth factor-1 levels are associated with high comorbidity of metabolic disorders in obese subjects: A Japanese single-center, retrospective study