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Microglia-mediated inflammation and neural stem cell differentiation in Alzheimers disease: possible therapeutic role of K(V)1.3 channel blockade

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CSE, cystathionine--lyase

Nonetheless, the current data point to a model where heme intermediates are channeled within multi-enzyme complexes, thus allowing tight control of heme synthesis, protecting cellular compartments from deleterious side reactions with reactive heme intermediates, and maintaining high rates of heme synthesis by keeping heme intermediates localized to specific subcellular regions

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