The mechanisms underlying these improvements are well-documented, and the clinical evidence supporting them is stronger than what exists for many mainstream skincare ingredients
After a follow-up visit 6 months later (from initial presentation), Helen's RF and CRP levels remained above normal, and she continued to have severe joint pain and radiographic evidence of progressive joint damage despite the increase in her dosage of methotrexate 3 months earlier
Proc Natl Acad Sci USA (2019) 116:151409
Supports Heart and Vascular Health*
In both male and female GHRKO mice, disruption of the GH/IGF-1 axis from birth results in mice that are remarkably long lived, but temporal disruption of this pathway in young adults (aGHRKO mice) improves lifespan only in females 17 , an observation which is consistent with the beneficial effects of targeting IGF-1R signaling post-development on female healthspan and aging in this study
Age As we age, our natural production of glutathione tends to decline