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Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology

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Outcome measures include neurological severity scoring, rotarod and beam walk performance, histological assessment of lesion volume, and immunohistochemistry for axonal markers and myelin basic protein

While eumelanin shows photoprotective capacity against ultraviolet (UV) [15], in contrast pheomelanin is weakly photoprotective and highly phototoxic, enhancing the UV-induced production of reactive oxygen species (ROS) and further damage of cells [16]

However, very long-term data spanning years to decades does not yet exist

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