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That conversion is inefficient

E., & Minich, D

This phosphorylation increases the affinity of -arrestin for the receptor, resulting in uncoupling of the subunit of the heterotrimeric G-protein from the receptor, producing desensitization

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Classically, this effect is attributed to the fact that the phosphate form of selenium, which is essential for some steps of the gene transcription for Se-GSH-Px synthesis, would be more readily available from selenite than from selenomethionine (Yasumoto et al., 1979