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Future research should focus on elucidating their mechanisms of action, optimizing extraction and synthesis methods, and conducting comprehensive toxicological assessments to facilitate their safe and effective utilization in healthcare and industry

Separation Sci

Several mutations in the bilirubin UDP-glucuronosyltransferase ( UGT1 ) gene of CN1 and CN2 patients have been identified, which result in complete inactivation of this enzyme in CN1 patients and markedly reduced glucuronidation in CN2 patients

Marriott, J