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2018 Jul 4;9:819

Key mechanisms: Directly inhibits NF-B the central transcription factor governing the body's inflammatory cascade Suppresses MAP kinase signalling pathways Reduces pro-inflammatory cytokines including TNF-, IL-1, and IL-6 Acts via PepT1 transporters in intestinal epithelial and immune cells, targeting gut-resident inflammation at the tissue level The evidence: A landmark study published in Gastroenterology demonstrated that nanomolar concentrations of KPV inhibit NF-B and MAP kinase inflammatory pathways and reduce pro-inflammatory cytokine secretion and that oral administration of KPV reduces the incidence of chemically induced colitis in mice as measured by both histology and cytokine expression

Intramuscular (IM): This requires a longer needle to deliver the solution directly into the muscle tissue

Moreover, some in vivo studies show that the peptide may actually reduce growth in tested animals due to the suppressive effect of this research peptide on the natural production of growth hormone