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Liu L, Zhou X, Zhang Y, Liu Y, Yang L, Pu J, Zhu D, Zhou C et al (2016) The identification of metabolic disturbances in the prefrontal cortex of the chronic restraint stress rat model of depression

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Neurons pretreated with Dihexa demonstrate significantly enhanced survival when exposed to reactive oxygen species, excitotoxic glutamate concentrations, or metabolic impairment compared to untreated controls

Treatment may involve managing symptoms and ensuring proper hydration