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doi:10.1371/journal.pone.0101320

The honest summary: this isn't a compound with five large randomized controlled trials behind it

Although thymosin beta4 is considered non-toxic, its involvement in angiogenesis and cell proliferation necessitates further investigation for long-term human safety. Xu et al., Peptides Sourcing and Purity Due to its legal gray area, most TB500 available for purchase is sold as a research chemical and not regulated for pharmaceutical quality

Controlled matrix remodeling: GHK-Cu finely modulates the activity of matrix metalloproteinases (MMPs), the enzymes responsible for the degradation of collagen and elastin