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Estimates suggest only about 50% or less is absorbed by the body

Mitochondrial Pathways

Key Benefits and Uses Treatment of Pernicious Anemia: Essential for patients whose bodies lack the "intrinsic factor" needed for B12 absorption

Unverified anecdotal reports from online forums mention various effects, though these cannot be confirmed without proper clinical investigation and may not represent causal relationships: Unverified reports of hormonal changes : Some users mention changes in libido or sexual function, though no causality has been established Theoretical cardiovascular concerns : Based on its purported vascular effects, though no clinical evidence exists Injection site reactions : Pain, redness, or swelling when administered subcutaneously Gastrointestinal symptoms : Nausea or abdominal discomfort in some reports Unknown long-term effects : No data exists on prolonged use or cumulative toxicity A significant safety concern involves product quality and contamination

It helps restore natural function

in this form it is essential for conversion of methylmalonate to succinate and synthesis of methionine from homocysteine (a reaction which also requires folate)