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The CNS GLP- 1 receptors are not necessary for the physiological regulation of blood glucose levels by endogenous GLP- 1 or the pharmacological control of glucose homeostasis that depends on GLP- 1 receptors, although further research is needed to investigate the possible role of GLP- 1 receptors expressed outside the beta cell, including within the enteric and peripheral nervous systems, in improving beta cell function through enteral glucose mediation [70, 84]

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Wattenberg., Isolation and Identification of Kahweol Palmitate and Cafestol Palmitate as Active Constituents of Green Coffee Beans That Enhance Glutathione S-Transferase Activity in the Mouse, A merican Association for Cancer Research , April 1982, 42: 1193-1198, Case of Poisoning by Aconite

The isomerization of p-tau at Thr 231 -Pro 232 from cis to trans , promotes both dephosphorylation of tau by PP2A and microtubule stabilization (99)