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Disturbed genomic integrity induces oxidative genetic damage, DNA oxidation, the activation of proto-oncogenes, and the inactivation tumour suppressor genes leading to proliferative effects and mutagenesis (113, 114)

Under oxidative stress, thiol groups of cysteine residues are oxidized to form reversible intramolecular disulfide bonds (SS) and cysteine sulfenic acids (CysSOH) or irreversible products such as sulfinic acids (CysSO 2 H) and sulfonic acids (CysSO 3 H) (Kanemura et al

This stem cell involvement may explain reports of tissue regeneration rather than just scar formation

It may have been reviewed by a licensed physician, but is not intended to serve as a substitute for professional medical advice

2) revealed that expression of these genes were not different between WT and KO livers in any diet groups

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