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Description

Br J cancer

a diuretic medication that appears to lower APOE4 transcription in mice and reduce Alzheimers risk in patients taking it

Nature 532, 6468

Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie 133: 111083

These biologically active compounds can disrupt immune signaling, mitochondrial energy production, gut barrier integrity, neurological regulation, and detoxification pathways

It also suppressed the expression of MyD88 in the UUO model, leading to decreased expression of fibrosis biomarkers such as -smooth muscle actin, vimentin, and connective tissue growth factor [244]