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OA chondrocytes displayed reduced mitochondrial DNA content, mitochondrial dysfunction, and diminished expression of NRF2 which regulates the transcription of oxidoreductase genes 89

E., & Houtkooper, R

Stain Comm

This metabolic indolence favours antibiotic tolerance and persister formation, as most antibiotics target growth-centred processes

This can feel like a constant, annoying heat and can get worse when doing things like walking, working out, or having sex

Joshua Kritzer, an associate professor of chemistry at Tufts University, says the study offers evidence that the stapled peptide approach is worth pursuing and could lead to new drugs that interfere with specific protein interactions