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The development of new antifungal drugs for aspergillosis includes Re-zafungin (CD101-IV), a novel echinocandin with unique pharmacokinetic properties that allows for weekly dosing and shows effective in vitro and in vivo activity against multiple Aspergillus species (Sandison et al., 2017

doi:10.1056/nejm199201303260504

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In terms of oxidative stress markers, CMH@lip@Res-TCeO 2 markedly decreased MDA levels and LDH release while enhancing GSH and SOD activity

A: Multiple pathways: GH receptor upregulation, nitric oxide system modulation, VEGF-promoted angiogenesis, and direct inflammatory cytokine interaction