Homozygous L2HGDH mutations in germline transmission cause a disease named 2-hydroxyglutaric aciduria (L-2-HGA) 92
Second, it reshapes MAPK signaling in a way that may steer cells away from acute inflammation and toward recovery
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At the beginning of the study, the participant reported occasional sleep disturbances, mild motor symptoms, mild anxiety and depression symptoms, and difficulties maintaining normal blood glucose levels
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